In the United States, there are 1 million pregnancies lost every year, and 26,000 happen after 20 weeks gestation, also known as still births. Doctors are still trying to find out why this happens.

Doctors at the University of Colorado, Denver School of Medicine are part of a research effort sponsored by the National Institutes of Health. Denver is one of four sites across the country that will be hosting the EAGeR trial. EAGeR stands for effects of aspirin in gestation and reproduction.

Researchers will be looking at the possible positive effects of taking low dose aspirin before and during pregnancy.

Dr. Anne Lynch is the principal investigator with the Denver trial.

"The hypothesis is the women who receive a low dose of aspirin will have better outcomes than the women who receive the placebo and this is really based on the fact that aspirin decreases the stickiness of platelets and so it improves the circulation in the intrauterine environment around the time of implantation and conception," Lynch said.

Researchers are enrolling participants right now. They are looking for women 18-40 years old, who have had a previous pregnancy loss and are hoping to become pregnant again.

Study participants are able to return to their use their own providers for regular prenatal care.

Anyone interested in participating should call 303-724-3525 or e-mail eager.trial@ucdenver.edu.