Lakewood Police officers were called to the Nite Owl Sports Bar & Grill at Wadsworth Boulevard and Mississippi Avenue around 1:30 a.m.
The unidentified man was asked to leave the bar "after becoming belligerent with other patrons" according to a press release. A short time later the victim returned and was again walked out of the bar.
Investigators say he got into a fight with two other men and later died at a local hospital.
One of the two suspects who police say were involved in the fight, Thomas Perez, has been arrested on suspicion of 2nd degree murder and is being held in the Jefferson County Jail.
Police are asking for the public's help locating the other man, Vicente Baros, who is also wanted for 2nd degree murder.
Anyone with information about the case is asked to call the Lakewood Police Department at 303-987-7111.
(KUSA-TV © 2012 Multimedia Holdings Corporation)