Six people were inside the home at 14065 East 26th Ave. when the fire started.
According to Aurora Fire the surviving 5 adults were transported to an area hospital due to minor smoke inhalation. The youngest transported is 19 years old.
The age of the man who died has not been released.
Witnesses say flames were seen coming from the roof of the two-story residence. The cause of the fire is under investigation.
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