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It begged Denver Broncos head coach John Fox to start Tim Tebow at quarterback instead of Kyle Orton.
INTERACTIVE: It's Tebow Time
Shortly after it went up, the Broncos reached 1-4 and then Tebow took over and led the team to the playoffs.
As the Broncos have evolved, so has the sign.
On Monday, the huge LED sign said, "Tebow's trigger is right on target," referring to John Elway's request that Tebow throw the ball during Sunday night's game.
Tebow threw for 316 yards and his 80-yard pass in overtime won the game for the Broncos over the Pittsburgh Steelers.
The people behind the sign are not Christian or a conservative group plugging Tebow's faith.
It's three Muslim brothers who are just big fans of Tebow and the Broncos.
"It adds to the fun, at least for us," Tariq Suleiman said.
"We wanted to be part of the excitement," Mohammad Suleiman said.
After Sunday night's thrilling overtime victory, the Suleiman brothers' latest message asks doubters, "Now Do You Believe" in Tebow?
"For me personally, I never doubted him. I knew he could pull off a Steelers win," Tariq said.
The Suleiman brothers have been creating new messages after each game, all from an office which has a window view of the sign.
Mohammad Suleiman is the youngest at 26, Ali, 28, is the middle brother, and Tariq, 30, comes up with most of the messages.
They all sell wholesale goods at their father's store which is next to the billboard.
As most fans know, Tebow is a devout Christian who thanks the Lord during most interviews.
The Suleiman brothers are devout Muslims, also proud of their faith.
"We do like the fact that he practices what he preaches," Mohammad Suleiman said.
"I am also a big believer in God as a Muslim, there are some differences but when Muslims and Christians get together, miracles can occur. We just had the Mile High miracle!" Tariq Suleiman said.
After Tebow threw for 316 yards last night, people quickly made the religious connection to John 3:16, which is Tebow's favorite Bible verse.
Tebow also wore the verse on his eye black when he was quarterback in college at the University of Florida.
After the connection surfaced Monday morning, John 3:16 became the most searched Google term on Monday.
"I went to check the Quran, chapter 3, verse 16 to see what it said, and it talks about salvation and believing in God, very similar to what the Bible says," Mohammad Suleiman said.
But the Suleimans say they didn't start running the billboards for religious reasons, it was all about rallying for their favorite quarterback and team.
"It's been great, obviously with the wins, and the way the fans have been coming in and reacting, they've been coming in and thanking us," Mohammad Suleiman said.
"We love the Denver Broncos, we've always been fans, and this year has been just an amazing year," Tariq Suleiman said.
9NEWS got a preview of the next sign the brothers will unveil. You can see it tonight on 9NEWS at 9 and 10 p.m.
(KUSA-TV © 2012 Multimedia Holdings Corporation)